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CRC1366

Vascular Control of Organ Function

Jun.-Prof. Dr. Roxana Ola

Cardiovascular Pharmacology, European Center for Angioscience

Medical Faculty Mannheim, Heidelberg University

roxana.ola(at)medma.uni-heidelberg.de

Professional Career

Since 2019

Junior Professor

for Cardiovascular Pharmacology, European Center for Angioscience,
Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

2019 -2019

Visiting Professor

Faculty of Medicine, Transylvania University, Brasov, Romania

2013 - 2018

Postdoctoral Associate

Yale Cardiovascular Research Center, Yale University, New Haven, USA

2005 - 2006

Visiting Scholar

Karolinska Institutet, Stockholm, Sweden

2012

Ph.D. in Epigenetics

Babes-Bolyai University

2012

Ph.D. in Development Biology

Helsinki University

Selected Publications

Genet G, Boye K, Mathivet T, Ola R, Zhang F, Dubrac A, Li J, Genet N, Geraldo LH, Benedetti L, Künzel S, Pibouin-Fragner L, Thomas J and Eichmann E: Endophilin-A2 dependent VEGFR2 Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis. Nat Commun, 10:2350, 2019.

Zhang F, Zarkada G, Han J, Li J, Dubrac A, Ola R, Genet G, Boyé K, Michon P, Künzel SE, Camporez JP, Singh AK, Fong G-H, Simons M, Tso P, Fernández-Hernando C, Shulman GI, Sessa WC, Eichmann A: Lacteal junction zippering protects against diet-induced obesity. Science, 361:599-603, 2018.

Kraehling JR, Chidlow JH, Rajagopal C, Sugiyama MG, Fowler JW, Lee MY, Zhang X, Ramírez-Hidalgo CM, Park EJ, Tao B, Chen K, Kuruvilla L, Larriveé B, Folta-Stogniew E, Ola R, Rotllan N, Zhou W, Nagle MW, Herz J, Williams KJ, Eichmann A, Lee WL, Fernández-Hernandoand C, Sessa WC: Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells. Nat Commun, 7:13652, 2016.

Dubrac A, Genet G, Ola R, Zhang F, Pibouin-Fragner L, Han J, Zhang J, Thomas JL, Chedotal A, Schwartz MA, Eichmann A: Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization. Circulation, 133:409-21, 2016.

Fortuna V, Pardanaud L, Brunet I, Ola R, Ristori E, Santoro MM, Nicoli S, Eichmann A: Vascular Mural Cells Promote Noradrenergic Differentiation of Embryonic Sympathetic Neurons. Cell Rep, 11:1786-96, 2015.

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